Hereditary Alpha Tryptasemia, or HAT, has also been called familial tryptasemia and hypertryptasemia.
HAT is caused by having 2 or more copies of the TPSAB1 gene on the chromosome 16p13.3 (source). A person whose symptoms have manifested from HAT has Hereditary Alpha Tryptasemia Syndrome, or HATS. This website focuses on people experiencing HATS and its co-morbidities.
Fewer than 500 people with HAT have been identified around the world--not all of whom experience HATS. However, the prevalence of HAT is considered to be between 3-5% of Caucasians.
If you suspect you may have Hereditary Alpha Tryptasemia Syndrome, see this article, "Confirming whether You Have HATS."
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